• Ellaine Salvador, Winfried Neuhaus, Carola Y. Förster:"In vitro traumatic brain injury model through stretch injury using brain microvascular endothelial cells", J. Vis. Exp., accepted (2013).
  

• Serge C. Thal, Eva-Verena Schaible, Winfried Neuhaus, David Scheffer, Moritz Brandstetter, Kristin Engelhard, Christian Wunder, Carola Y. Förster:"Inhibition of protesomal glucocorticoid receptor degradation restores dexamethasone-mediated stabilization of the blood-brain-barrier after traumatic brain injury", Crit. Care Med. 41, 1305-1315 (2013).

• Sergey Shityakov, Winfried Neuhaus, Thomas Dandekar, Carola Förster:"Analyzing molecular polar surface descriptors to predict blood-brain barrier permeation", Int. J. Comp. Biol. Drug Design 6, 146-156 (2013).
  

• Winfried Neuhaus, Fabian Samwer, Steffen Kunzmann, Ralf M. Muellenbach, Michael Wirth, Christian P. Speer, Norbert Roewer, Carola Y. Förster:"Lung endothelial cells strengthen, but brain endothelial cells weaken barrier properties of a human alveolar epithelium cell culture model", Differentiation 84, 294-304 (2012).

• Winfried Neuhaus*, Jana Mandikova, Rita Pawlowitsch, Birgit Linz, Barbara Bennani-Baiti, Regina Lauer, Bodo Lachmann, Christian R. Noe*: "Blood-brain barrier in vitro models as tools in drug discovery: Assessment of the transport ranking of antihistaminic drugs", Pharmazie 67, 432-439 (2012).

• Winfried Neuhaus*, Malgorzata Burek, Cholpon S. Djuzenova, Serge Thal, Hermann Koepsell, Norbert Roewer, Carola Foerster*:"Addition of NMDA-receptor antagonist MK801 during oxygen/glucose deprivation moderately attenuates the up-regulation of glucose uptake after subsequent reoxygenation in brain endothelial cells", Neurosci. Lett. 506, 44-49 (2012).

• Winfried Neuhaus, Martin A Schick, Raphael R Bruno, Bianca Schneiker, Carola Foerster, Norbert Roewer, Christian Wunder:"The effects of colloid solutions on renal proximal tubular cells in vitro", Anesthesia & Analgesia 114, 371-374 (2012).
  

• Winfried Neuhaus, Michael Freidl, Phillip Szkokan, Michael Berger, Michael Wirth, Johannes Winkler, Franz Gabor, Christian Pifl, Christian R. Noe:"Effects of NMDA-receptor modulators on a blood-brain barrier in vitro model", Brain Res. 1394, 49-61 (2011).

• Wolfgang Bueter, Norman R Saunders, Carina Mallard, Hans-Christian Bauer, Helen B Stolp, Annemieke Kavelaars, Olaf Dammann, NEUROBID consortium: "NEUROBID-an EU-funded project to study the developing brain barriers", Int. Dev. Neurosci. 28, 411-412 (2010).

• Verena Poetsch, Winfried Neuhaus, Christian R. Noe:"Serum-derived Immunglobulins neutralize adverse effects of amyloid β peptide on the integrity of a blood-brain barrier in vitro model", J. Alzheimers Disease 21, 303-314 (2010).

• Winfried Neuhaus, Martina Stessl, Elisabeth Strizsik, Barbara Bennani-Baiti, Michael Wirth, Stefan Toegel, Maaya Modha, Johannes Winkler, Franz Gabor, Helmut Viernstein, Christian R. Noe:"Blood-Brain Barrier Cell Line PBMEC/C1-2 possesses functionally active P-glycoprotein", Neurosci. Lett. 469, 224-228 (2010).

• Verena E Plattner, Bettina Germann, Winfried Neuhaus, Christian R. Noe, Franz Gabor, Michael Wirth:"Characterization of two blood-brain barrier mimicking cell lines: distribution of lectin binding sites and perspectives for drug delivery", Int. J. Pharm. Vol 387, 34-41 (2010).
  

• Verena Poetsch, Barbara Bennani-Baiti, Winfried Neuhaus, Eva-Maria Muchitsch, Christian R. Noe:"Serum-derived Immunoglobulins alter Amyloid-β transport across a blood-brain barrier in vitro model", Pharmazie 65, 267-273 (2010).
  

• Winfried Neuhaus, Bettina Germann, Verena E. Plattner, Michael Wirth, Franz Gabor, Christian R. Noe:"Alteration of the glycocalyx of two blood-brain barrier mimicking cell lines is inducible by glioma conditioned media", Brain Res. Vol 1279, 82-89 (2009).

• Winfried Neuhaus, Michael Wirth, Verena E. Plattner, Bettina Germann, Franz Gabor, Christian R. Noe:"Expression of Claudin-1, Claudin-3 and Claudin-5 in human blood-brain barrier mimicking cell line ECV304 is inducible by glioma conditioned media", Neurosci. Lett. Vol 446 Issues 2-3, 59-64 (2008).

• Winfried Neuhaus, Gabriele Trauner, Daniela Gruber, Silvester Oelzant, Waltraud Klepal, Brigitte Kopp, Christian R. Noe:"Transport of a GABA_A-receptor modulator and its derivatives derived from Valeriana officinalis L. s.l. across an in vitro cell culture model of the blood-brain barrier" Planta Med. 74, 1338-1344 (2008).

• Winfried Neuhaus, Verena E. Plattner, Michael Wirth, Bettina Germann, Bodo Lachmann, Franz Gabor, Christian R. Noe:"Validation of in vitro cell culture models of the blood-brain barrier: Tightness characterization of two promising cell lines", J. Pharm. Sci. Vol 97, 5158-5175 (2008).
  

• Bettina Germann, Winfried Neuhaus, Renate Hofer-Warbinek, Christian R. Noe:"Applying blood-brain barrier in vitro models to study the influence of drugs on endothelial cells – effects of selected COX-inhibitors.“ Pharmazie Vol 63 Issue 4, 303-307 (2008).

• Winfried Neuhaus, Regina Lauer, Silvester Oelzant, Urs P. Fringeli, Gerhard F. Ecker, Christian R. Noe:"A novel flow based hollow-fiber blood-brain barrier in vitro model with immortalised cell line PBMEC/C1-2", J Biotechnol. Vol 125 Issue 1, 127-141 (2006).
  

• Winfried Neuhaus, Elisabeth Bogner, Michael Wirth, Joanna Trzeciak, Bodo Lachmann, Franz Gabor, Christian R. Noe:"A novel tool to characterize paracellular transport: The APTS-dextran ladder", Pharm. Res. Vol 23 Issue 7, 1491-1501 (2006).
  

• Winfried Neuhaus,  Joanna Trzeciak, Regina Lauer, Bodo Lachmann, Christian R. Noe:"APTS-labeled dextran ladder: A novel tool to characterize cell layer tightness", J Pharm. Biomed. Anal. Vol 40 Issue 4, 1035-1039 (2006).
  

• Winfried Neuhaus*, Senad Novalin, Mario Klimacek, Barbara Splechtna, Inge Petzelbauer, Alexander Szivak, Klaus D. Kulbe:"Optimization of an innovative hollow-fiber process to produce lactose-reduced skim milk", Appl. Biochem. Biotechnol. Vol 134 Issue 1, 1-14 (2006).
  

• Senad Novalin, Winfried Neuhaus*, Klaus D. Kulbe:"A new innovative process to produce lactose-reduced skim milk", J Biotechnol. Vol 119, 212-218 (2005).

* corresponding author

Book contributions

• Winfried Neuhaus, Malgorzata Burek, Christian Wunder, Carola Y. Förster: "Novel strategies to restore blood-brain barrier integrity after brain injury", In: Blood Brain Barrier: New Research, P.A. Montenegro, S.M. Juárez (eds.), Nova Science, 1st Edition, Hauppauge NY, chapter 5, ISBN 978-1-62100-766-1, pages 145-172 (2012). - OPEN ACCESS - DOWNLOADABLE

• Winfried Neuhaus, Christian R. Noe: "Transport at the Blood-Brain Barrier", In: Transporters as drug carriers, G.F. Ecker, P. Chiba (eds.), Whiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, pages 263-298 (2009).

Poster presentations and Abstracts

• Neuhaus, W., Gaiser, F., Schlegel, N., Macrez, R., Vivien, D., Foerster, C.Y.:"NMDAR subunit NR1 is essential for blood-brain barrier damage and cell motility in an in-vitro mouse stroke model", abstract for a talk at the 15th Transporter-Meeting in Bad Herrenalb (15. Bad Herrenalber Transportertage), Bad Herrenalb, Germany, 13th-15th May 2013.

• Salvador, E., Neuhaus, W., Koepsell, H., Foerster, C.:"Sodium-dependent glucose transporter SGLT1 expression in the blood-brain barrier as a result of injury using an in-vitro traumatic brain injury model", abstract for a talk at the 15th Transporter-Meeting in Bad Herrenalb (15. Bad Herrenalber Transportertage), Bad Herrenalb, Germany, 13th-15th May 2013.

• Neuhaus, W., Burek, M., Foerster, C.Y.:"PPARα agonists stabilize the blood-brain barrier after in vitro stroke by inhibition of MMP and proteasome activity", abstract for a talk at the symposium "Beating the Blood-Brain and other Blood Barriers", Lisbon, Portugal, 6th-8th February 2013.

• Bruno, R.R., Neuhaus, W., Neuhoff, A., Roewer, N., Schick, M.A., Wunder, C.:"The impact of hydroxyethylstarch 130/0.4 on human proximal tubular cells in vitro", ESICM 2012, 25th Annual Congress of the European Society of Intensive Care Medicine, Lisbon, Portugal, 13th-17th October 2012.

• Neuhaus, W., Förster, C.:"Effects of synthetic glucocorticoids on fetal and newborn BBB maturation: implications in adverse health consequences", abstract for a talk at the 15th International Symposium Signal transduction in the blood-brain barriers, Potsdam, Germany, 13th-16th September 2012.

• Neuhaus, W., Burek, M., Roewer, N., Förster, C.:"Inhibition of OGD induced and astrocyte enhanced blood-brain barrier breakdown by specific receptor modulators", abstract for poster presentaton at the 15th International Symposium Signal transduction in the blood-brain barriers, Potsdam, Germany, 13th-16th September 2012.

• Burek, M., Salvador, E., Neuhaus, W., Shityakov, S., Förster, C.:"Generation of an immortalized murine brain microvascular endothelial cell line as an in vitro blood-brain barrier model" posterpresentation at 3rd International Conference Strategies in Tissue Engineering, Würzburg, Germany, 23rd-25th May 2012.

• Neuhaus, W.,  Neuhoff, A., Burek, M., Roewer, N., Foerster, C.Y.:"The role of astrocytes in a mouse blood-brain barrier in vitro model of oxygen/glucose deprivation" abstract for a talk at the 3rd International Conference Strategies in Tissue Engineering, Würzburg, Germany, 23rd-25th May 2012.

• Neuhaus, W., Roewer, N., Foerster, C.:"Interplay of astrocytes and receptor ligands in a mouse blood-brain barrier in vitro model of oxygen/glucose deprivation", abstract for a talk at the 4th Transporter-Meeting in Bad Herrenalb (14. Bad Herrenalber Transportertage), Bad Herrenalb, Germany, 14th-16th May 2012.

• Salvador, E., Neuhaus, W., Wais, S., Thal, S., Foerster, C.:"Sodium-dependent glucose transporters expression in the blood brain barrier after injury and its contribution to edema formation", posterpresentation at the SFB-Meeting, RVZ Würzburg, Germany, 19th-21th April 2012.
  

• Sebastiani, A., Yang, D., Luh, C., Koepsell, H., Neuhaus, W., Werner, C., Engelhard, K., Förster, C., Thal, S.C.:"Deficiency in Sodium-Dependent Glucose Transporter 1 has no effect on brain edema formation after traumatic brain injury", EURONEURO 2012, 7th International Update on Interdisciplinary Neursoscience, Vienna, Austria, 16th-18th February 2012.

• Neuhaus, W., Burek, M., Djuzenova, C.S., Koepsell, H., Roewer, N., Förster, C.Y:"Oxygen/glucose deprivation induced upregulation of  glucose uptake is inhibitable by a NMDAR antagonist in a blood-brain barrier in vitro model", 9th International Conference on Cerebral Vascular Biology, Leiden, Netherlands, 21th-25th June 2011.
  

• Neuhaus, W., Burek, M., Djuzenova, C.S., Koepsell, H., Roewer, N., Förster, C.Y:"NMDA-receptor antagonist MK801 attenuates up-regulation of glucose uptake after oxygen/glucose deprivation in a blood-brain barrier in vitro model", 8th International Symposium on the Biology of Endothelial Cells, ETH Zurich main campus, Zurich, Switzerland, 15th-18th June 2011.

• Bruno, R.R., Schick, M.A., Neuhaus, W., Roewer, N., Foerster, C., Wunder, C.:"HES 130/0,4 und Gelatine schädigen proximale Nierentubuluszellen in vitro",  DEUTSCHER ANÄSTHESIEKONGRESS 2011, Hamburg, Germany, 14th-17th May 2011.
  

• Gebhard, C., Strizsik, E., Winkler, J., Neuhaus, W., Marchetti-Deschmann, M., Allmaier, G., Hofer-Warbinek, R., Noe, C.R.:"Differential proteome analysis of BBB endothelia cells in an in vitro model", 4^th Central and Eastern European Proteomics Conference, Vienna, Austria, 29th August-1 September 2010.
  

• Fillafer, C., Prantl, M., Ratzinger, G., Neumann, J., Schneider, M.F., Neuhaus, W., Hofer-Warbinek, R., Wirth, M., Gabor, F.:"Microfluidics on a chip - impact of flow on the particle-cell interaction", 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Valletta, Malta, 8th-11th March 2010.
  

• Fillafer, C., Prantl, M., Ratzinger, G., Neumann, J., Schneider, M.F., Neuhaus, W., Hofer-Warbinek, R., Wirth, M., Gabor, F.:"Microfluidic system to study the impact of flow on particle-cell interactions", DPhG Doktorandentagung Pichlarn, Austria, 18th-21st November 2009.
  

• Neuhaus, W., Subileau, E., Chesne, C., Gruber, D., Tögel, S., Klepal, W., Viernstein, H., Noe, C.R.:"A novel Blood-Brain Barrier in vitro Model based on Primary Rat Cells", posterpresentation on the 12th International Symposium for Signalling at the Blood-Brain and Retinal Barriers, London, UK, 9th-11th September 2009.

• Neuhaus, W., Stessl, M., Strizsik, E., Bennani-Baiti, B., Wirth, M., Mandikova, J., Pawlowitsch, R., Tögel, S., Gabor, F., Viernstein, H., Noe, C.R.:"Functionality of P-glycoprotein in the Blood-Brain Barrier mimicking cell line PBMEC/C1-2", posterpresentation on the 21th Scientific Congress of the Austrian Pharmaceutical Society, Vienna, Austria, 16th-18th April 2009; Abstract in: Sci. Pharm. 77 (1), PO-20 (2009).

• Novakova, I., Neuhaus, W., Sonnenberg, M., Noe, C.R.:"Transport of NSAIDs across the Blood-Brain Barrier in vitro", posterpresentation on the 21th Scientific Congress of the Austrian Pharmaceutical Society, Vienna, Austria, 16th-18th April 2009; Abstract in: Sci. Pharm. 77 (1), PO-21 (2009).

• Freidl, M., Neuhaus, W., Wirth, M., Gabor, F., Noe, C.R.:"Functionability of NMDA-Receptors in an in vitro model of the Blood-Brain-Barrier", posterpresentation on the 21th Scientific Congress of the Austrian Pharmaceutical Society, Vienna, Austria, 16th-18th April 2009; Abstract in: Sci. Pharm. 77 (1), PO-19 (2009).

• Neuhaus, W., Germann, B., Plattner, V.E., Gabor, F., Wirth, M., Noe, C.R.:"Glioma conditioned media cause alterations of lectin-binding capacities of two blood-brain barrier mimicking cell lines", posterpresentation at the Gordon Research Conference "Barries of the CNS", Tilton School, Tilton (NH, USA), June 22-27, 2008.

• Plattner, V.E., Germann, B., Neuhaus, W., Gabor, F., Noe, C.R., Wirth, M.:"Lectin-mediated delivery at the blood-brain barrier: Evaluation of the lectin binding pattern of two blood-brain barrier in vitro models " posterpresentation at the 6th PBP World Meeting, Barcelona, Spain, 7th-10th April 2008.
  

• Plattner, V.E., Neuhaus, W., Germann, B., Gabor, F., Noe, C.R., Wirth, M.:"Characterization of two blood-brain barrier in vitro  models: distribution of lectin binding sites and perspectives for drug delivery", posterpresentation on the 7th Conference and Workshop on Biological Barriers and Nanomedicine - Advanced Drug Delivery and Predictive non vivo Testing Technologies, University of Saarland, Saarbrücken, Germany, 20th-29th February 2008.

• Cohrs B. and Bethke M., Neuhaus, W., Lachmann, B., Noe, C.R., Clement, B.:"Transport of Pentamidine, Diminazene and derivatives across a blood-brain barrier in vitro model", posterpresentation on the DPHG-symposium 2007, Erlangen, Germany, 10th-13th October 2007.

• Trauner, G., Neuhaus, W., Noe, C.R., Kopp, B.:"The transport of GABA_A-receptor modulators derived from Valeriana officinalis L", posterpresentation on the International Congress and 55th Annual Meeting of the Society for Medicinal Plant Research in Graz, Austria, 2nd-6th September 2007.

• Neuhaus, W., Plattner, V.E., Wirth, M., Germann, B., Lachmann, B., Gabor, F., Noe, C.R.:"Tightness characterisation of a blood-brain barrier in vitro model based on human cell line ECV304", posterpresentation on the 3rd Pharmaceutical Sciences World Congress, Amsterdam  22nd-25th April 2007, click for details on: Abstract PA-T-18.

• Neuhaus, W., Plattner, V.E., Wirth, M., Germann, B., Lachmann, B., Gabor, F., Noe, C.R.:"Tightness characterisation of a blood-brain barrier in vitro model based on human cell line ECV304", posterpresentation on the Pre-Satellite Meeting PhD and Post docs of the PSWC, Amsterdam  20th-21st April 2007, click for details on: Abstract DD-P-070.

• Neuhaus, W., Bogner, E., Wirth, M., Lachmann, B., Gabor, F., Noe, C.R.:"The APTS-dextran ladder: A novel tool to determine the tightness status of cell layers", posterpresentation on the 19th Scientific Congress of the Austrian Pharmaceutical Society, Innsbruck 2006; Abstract in: Sci. Pharm. 74 (2), S47 (2006).

• Neuhaus, W., Lauer, R., Oelzant, S., Fringeli, U.P., Ecker, G.F., Noe, C.R.:"A flow based hollow-fiber blood-brain barrier in vitro model with immortalised cell line PBMEC/C1-2", posterpresentation at the Gordon Research Conference "Barries of the CNS", Tilton School, Tilton (NH, USA), June 25-30, 2006.

• Neuhaus, W., Trzeciak, J., Lachmann, B., Noe, C.R.: "APTS-labeled dextrans: A new tool for characterizing cell layer's tightness", posterpresentation on "Peripheral markers of Blood-brain barrier failure III symposium", Cleveland (Ohio, USA) November 2004, Abstract in: Syllabus (2004).

• Pawlowitsch, R., Neuhaus, W., Lauer, R., Linz, B., Lachmann, B., Ecker, G. F., Noe, C. R.:"Permeation studies of a set of antihistaminic drugs with an in vitro blood-brain barrier model" posterpresentation on the EUFEPS 2004, Brussels October 2004, Abstract in: European Journal of pharmaceutical sciences, Volume 23, supplement 1, October 2004.

• Neuhaus W., Vienna/A, Trzeciak, J., Vienna/A, Lauer, R., Vienna/A, Lachmann, B., Vienna/A, Noe, C.R., Vienna/A: "Tightness Determination of two Blood-Brain Barrier Models: Correction by means of Capillary gel electrophoresis", posterpresentation on the Analytica 2004 conference, Munich 2004, Abstract in: http://va.gdch.de/wwwdata/abstracts/5553/5553_0178.pdf

• W. Neuhaus, R. Lauer, G.F. Ecker, C.R. Noe: “Ein dynamisches in vitro Modell der Blut-Hirn Schranke”, posterpresentation on the 17th Scientific Congress of the Austrian Pharmaceutical Society, Graz 2003; Abstract in: Sci. Pharm. 71, S61 (2003).

• T. Mayrhofer, W. Neuhaus, R. Lauer, G.F. Ecker, C.R. Noe: “Permeationsstudien einer Reihe von Glycin-Antagonisten an einem in vitro Modell der Blut-Hirn Schranke”, posterpresentation on the 17th Scientific Congress of the Austrian Pharmaceutical Society, Graz 2003; Abstract in: Sci. Pharm. 71, S60 (2003).

• J. Kainz, R. Lauer, W. Neuhaus, C.R. Noe, G.F. Ecker: “Physikochemische Charakterisierung einer Reihe von Glycinantagonisten zur Abschätzung ihrer Permeationseigenschaften in der Blut-Hirn Schranke”, posterpresentation on the 17th Scientific Congress of the Austrian Pharmaceutical Society, Graz 2003; Abstract in: Sci. Pharm. 71, S57 (2003).
  

• Novalin, S., Neuhaus, W., Weber, A. Kulbe, K.D.: Entwicklung eines neuartigen Enzym-Membranreaktors zur Hydrolyse von Lactose im Industriemaßstab.. In: Univ. f. Bodenkultur Wien, Tschechische Agraruniversität Prag, Univ. Westungarn (Hrsg.): Tagungsband, Boku-Kongress 'Leben und Überleben - Konzepte für die Zukunft', Abstracts, 219. 19-21 November 2001, Hofburg, Wien (2001).