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Recent publications could be found via this link: AIT publication data base
 

Peer-reviewed Publications


         § contributed equally to this work
          § contributed equally to this work

* corresponding author

Book contributions and Reviews


  • Serge C. Thal, Winfried Neuhaus: “The Blood-brain barrier as a target in traumatic brain injury treatment”, invited review in the Special Issue: The Blood-brain barrier in neurological diseases, Arch. Med. Res., 45(8), 698-710 (2014). 
  • Winfried Neuhaus, Christian R. Noe: "Transport at the Blood-Brain Barrier", In: Transporters as drug carriers, G.F. Ecker, P. Chiba (eds.), Whiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, pages 263-298 (2009).
Poster presentations and Abstracts


  • Schick, M.A., Neuhaus, W., Stein, F., Roewer, N., Wunder, C.:"Induktion der Autophagie hebt den HES-induzierten  Schaden in humanen proximalen Tubuluszellen der Niere (HK-2) in-vitro auf", abstract for a talk at the WAT 2016, Wuerzburg, Germany, 19th-20th February 2016.
  • Neuhaus, W., Gaiser, F., Kraemer, T., Membier, S., Mayrhofer, J., Docagne, F., Macrez, R., Vivien, D., Franz, J., Riethmüller, C., Mahringer, A., Subileau, E.A., Chesne, C,  Thal, S., Förster, C.Y.:" An in-vitro blood-brain barrier model for ischemia: Validation and Applicability", abstract for a talk at the 2nd Zing Barriers of the CNS Conference, Oropesa, Spain, 27th-30th September 2015.
  • Appelt-Menzelt, A., Neuhaus, W., Walles, H., Metzger, M.:"Differentiation of human multipotent and pluripotent stem cells to develop a human 3D in vitro blood brain barrier model", abstract for a talk at the 4th International Conference Strategies in Tissue Engineering, Würzburg, Germany, 10th-12th June 2015.
  • Neuhaus, W., Neuhoff, A., Subileau, E.A., Chesne, C., Foerster, C.Y.:"Effects of oxygen/glucose deprivation: Rat glioma versus primary glial cells", abstract for a talk at the 17th Transporter-Meeting in Bad Herrenalb (17. Bad Herrenalber Transportertage), Bad Herrenalb, Germany, 11th-13th May 2015.

  • Mencl, S., Neuhaus, W., Förster, C., Kleinschnitz, C.:"Antenatal inflammation leads to attenuated blood-brain barrier permeability after stroke in young adult mice", abstract for a poster at the European Stroke Organisation (ESO) Conference, Glasgow, Scotland, 17th-19th April 2015.

  • Neuhaus, W., Mencl, S., Kleinschnitz, C., Foerster, C.Y.: "Antenatal Inflammation Leads to Attenuated Blood-Brain Barrier Permeability after Stroke in Young Adult Mice", abstract and poster at the 16th International Symposium on Signal Transduction at the Blood-Brain and Blood-Retina Barriers, Dublin, Ireland, 11th-13th September 2014.
  • Bruno, R.R., Neuhaus, W., Roewer, N., Wunder, C., Schick, M.A.:"Die Molekülgröße und die Herstellungsgrundlage (Mais oder Kartoffel) haben keinen Einfluss auf die schädigende Wirkung von Hydroxyethylstärke (HES) auf proximale humane Nierentubulusepithelzellen in-vitro", abstract for a talk at the WAT 2014, Wuerzburg, Germany, 14th-15th February 2014.
  • Wollborn, J., Wunder, C., Stix, J., Neuhaus, W., Bruno, R., Flemming, S., Roewer, N., Schlegel, N., Schick, M.A.:"Phosphodiesterase-4-Inhibition vermindert den Leberzellschaden in der systemischen Inflammation in-vitro und in-vivo ohne Einfluss auf die Entzündungsreaktion und die Hämoxygenase-1 (HO-1)", abstract for a talk at the WAT 2014, Wuerzburg, Germany, 14th-15th February 2014.

  • Küstermann, J., Bauer, D., Neuhoff, A., Roewer, N., Muellenbach, R.M., Neuhaus, W.:"Hyperoxie induziert eine Steigerung der Barriere in einem humanen in-vitro Modell des Lungenalveolarepithels", abstract for a talk at the WAT 2014, Wuerzburg, Germany, 14th-15th February 2014.
  • Neuhaus, W., Neuhoff, A., Gaiser, F., Foerster, C.Y.:"Novel therapeutical in-vitro approaches for stroke treatment: The role of the tPA/PAI-1 axis at the blood-brain barrier", abstract and poster at the 16th International Symposium on Signal Transduction in the Blood-Brain Barriers, Sümeg, Hungary, 12th-14th September 2013.
  • Neuhaus, W., Gaiser, F., Schlegel, N., Macrez, R., Vivien, D., Foerster, C.Y.:"NMDAR subunit NR1 is essential for blood-brain barrier damage and cell motility in an in-vitro mouse stroke model", abstract for a talk at the 15th Transporter-Meeting in Bad Herrenalb (15. Bad Herrenalber Transportertage), Bad Herrenalb, Germany, 13th-15th May 2013.
  • Salvador, E., Neuhaus, W., Koepsell, H., Foerster, C.:"Sodium-dependent glucose transporter SGLT1 expression in the blood-brain barrier as a result of injury using an in-vitro traumatic brain injury model", abstract for a talk at the 15th Transporter-Meeting in Bad Herrenalb (15. Bad Herrenalber Transportertage), Bad Herrenalb, Germany, 13th-15th May 2013.
  • Neuhaus, W., Burek, M., Foerster, C.Y.:"PPARα agonists stabilize the blood-brain barrier after in vitro stroke by inhibition of MMP and proteasome activity", abstract for a talk at the symposium "Beating the Blood-Brain and other Blood Barriers", Lisbon, Portugal, 6th-8th February 2013.
  • Bruno, R.R., Neuhaus, W., Neuhoff, A., Roewer, N., Schick, M.A., Wunder, C.:"The impact of hydroxyethylstarch 130/0.4 on human proximal tubular cells in vitro", ESICM 2012, 25th Annual Congress of the European Society of Intensive Care Medicine, Lisbon, Portugal, 13th-17th October 2012.
  • Neuhaus, W., Förster, C.:"Effects of synthetic glucocorticoids on fetal and newborn BBB maturation: implications in adverse health consequences", abstract for a talk at the 15th International Symposium Signal transduction in the blood-brain barriers, Potsdam, Germany, 13th-16th September 2012.
  • Neuhaus, W., Burek, M., Roewer, N., Förster, C.:"Inhibition of OGD induced and astrocyte enhanced blood-brain barrier breakdown by specific receptor modulators", abstract for poster presentaton at the 15th International Symposium Signal transduction in the blood-brain barriers, Potsdam, Germany, 13th-16th September 2012.
  • Burek, M., Salvador, E., Neuhaus, W., Shityakov, S., Förster, C.:"Generation of an immortalized murine brain microvascular endothelial cell line as an in vitro blood-brain barrier model" posterpresentation at 3rd International Conference Strategies in Tissue Engineering, Würzburg, Germany, 23rd-25th May 2012.
  • Neuhaus, W.,  Neuhoff, A., Burek, M., Roewer, N., Foerster, C.Y.:"The role of astrocytes in a mouse blood-brain barrier in vitro model of oxygen/glucose deprivation" abstract for a talk at the 3rd International Conference Strategies in Tissue Engineering, Würzburg, Germany, 23rd-25th May 2012.
  • Neuhaus, W., Roewer, N., Foerster, C.:"Interplay of astrocytes and receptor ligands in a mouse blood-brain barrier in vitro model of oxygen/glucose deprivation", abstract for a talk at the 4th Transporter-Meeting in Bad Herrenalb (14. Bad Herrenalber Transportertage), Bad Herrenalb, Germany, 14th-16th May 2012.
  • Salvador, E., Neuhaus, W., Wais, S., Thal, S., Foerster, C.:"Sodium-dependent glucose transporters expression in the blood brain barrier after injury and its contribution to edema formation", posterpresentation at the SFB-Meeting, RVZ Würzburg, Germany, 19th-21th April 2012.
  • Sebastiani, A., Yang, D., Luh, C., Koepsell, H., Neuhaus, W., Werner, C., Engelhard, K., Förster, C., Thal, S.C.:"Deficiency in Sodium-Dependent Glucose Transporter 1 has no effect on brain edema formation after traumatic brain injury", EURONEURO 2012, 7th International Update on Interdisciplinary Neursoscience, Vienna, Austria, 16th-18th February 2012.
  • Neuhaus, W., Burek, M., Djuzenova, C.S., Koepsell, H., Roewer, N., Förster, C.Y:"Oxygen/glucose deprivation induced upregulation of  glucose uptake is inhibitable by a NMDAR antagonist in a blood-brain barrier in vitro model", 9th International Conference on Cerebral Vascular Biology, Leiden, Netherlands, 21th-25th June 2011.
  • Neuhaus, W., Burek, M., Djuzenova, C.S., Koepsell, H., Roewer, N., Förster, C.Y:"NMDA-receptor antagonist MK801 attenuates up-regulation of glucose uptake after oxygen/glucose deprivation in a blood-brain barrier in vitro model", 8th International Symposium on the Biology of Endothelial Cells, ETH Zurich main campus, Zurich, Switzerland, 15th-18th June 2011.
  • Bruno, R.R., Schick, M.A., Neuhaus, W., Roewer, N., Foerster, C., Wunder, C.:"HES 130/0,4 und Gelatine schädigen proximale Nierentubuluszellen in vitro",  DEUTSCHER ANÄSTHESIEKONGRESS 2011, Hamburg, Germany, 14th-17th May 2011.
  • Gebhard, C., Strizsik, E., Winkler, J., Neuhaus, W., Marchetti-Deschmann, M., Allmaier, G., Hofer-Warbinek, R., Noe, C.R.:"Differential proteome analysis of BBB endothelia cells in an in vitro model", 4th Central and Eastern European Proteomics Conference, Vienna, Austria, 29th August-1 September 2010.

  • Fillafer, C., Prantl, M., Ratzinger, G., Neumann, J., Schneider, M.F., Neuhaus, W., Hofer-Warbinek, R., Wirth, M., Gabor, F.:"Microfluidics on a chip - impact of flow on the particle-cell interaction", 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Valletta, Malta, 8th-11th March 2010.
  • Fillafer, C., Prantl, M., Ratzinger, G., Neumann, J., Schneider, M.F., Neuhaus, W., Hofer-Warbinek, R., Wirth, M., Gabor, F.:"Microfluidic system to study the impact of flow on particle-cell interactions", DPhG Doktorandentagung Pichlarn, Austria, 18th-21st November 2009.
  • Neuhaus, W., Subileau, E., Chesne, C., Gruber, D., Tögel, S., Klepal, W., Viernstein, H., Noe, C.R.:"A novel Blood-Brain Barrier in vitro Model based on Primary Rat Cells", posterpresentation on the 12th International Symposium for Signalling at the Blood-Brain and Retinal Barriers, London, UK, 9th-11th September 2009.
  • Neuhaus, W., Germann, B., Plattner, V.E., Gabor, F., Wirth, M., Noe, C.R.:"Glioma conditioned media cause alterations of lectin-binding capacities of two blood-brain barrier mimicking cell lines", posterpresentation at the Gordon Research Conference "Barries of the CNS", Tilton School, Tilton (NH, USA), June 22-27, 2008.
  • Plattner, V.E., Germann, B., Neuhaus, W., Gabor, F., Noe, C.R., Wirth, M.:"Lectin-mediated delivery at the blood-brain barrier: Evaluation of the lectin binding pattern of two blood-brain barrier in vitro models " posterpresentation at the 6th PBP World Meeting, Barcelona, Spain, 7th-10th April 2008.
  • Plattner, V.E., Neuhaus, W., Germann, B., Gabor, F., Noe, C.R., Wirth, M.:"Characterization of two blood-brain barrier in vitro  models: distribution of lectin binding sites and perspectives for drug delivery", posterpresentation on the 7th Conference and Workshop on Biological Barriers and Nanomedicine - Advanced Drug Delivery and Predictive non vivo Testing Technologies, University of Saarland, Saarbrücken, Germany, 20th-29th February 2008.
  • Cohrs B. and Bethke M., Neuhaus, W., Lachmann, B., Noe, C.R., Clement, B.:"Transport of Pentamidine, Diminazene and derivatives across a blood-brain barrier in vitro model", posterpresentation on the DPHG-symposium 2007, Erlangen, Germany, 10th-13th October 2007.
  • Trauner, G., Neuhaus, W., Noe, C.R., Kopp, B.:"The transport of GABAA-receptor modulators derived from Valeriana officinalis L", posterpresentation on the International Congress and 55th Annual Meeting of the Society for Medicinal Plant Research in Graz, Austria, 2nd-6th September 2007.
  • Neuhaus, W., Plattner, V.E., Wirth, M., Germann, B., Lachmann, B., Gabor, F., Noe, C.R.:"Tightness characterisation of a blood-brain barrier in vitro model based on human cell line ECV304", posterpresentation on the 3rd Pharmaceutical Sciences World Congress, Amsterdam  22nd-25th April 2007, click for details on: Abstract PA-T-18.
  • Neuhaus, W., Plattner, V.E., Wirth, M., Germann, B., Lachmann, B., Gabor, F., Noe, C.R.:"Tightness characterisation of a blood-brain barrier in vitro model based on human cell line ECV304", posterpresentation on the Pre-Satellite Meeting PhD and Post docs of the PSWC, Amsterdam  20th-21st April 2007, click for details on: Abstract DD-P-070.
  • Neuhaus, W., Bogner, E., Wirth, M., Lachmann, B., Gabor, F., Noe, C.R.:"The APTS-dextran ladder: A novel tool to determine the tightness status of cell layers", posterpresentation on the 19th Scientific Congress of the Austrian Pharmaceutical Society, Innsbruck 2006; Abstract in: Sci. Pharm. 74 (2), S47 (2006).
  • Neuhaus, W., Lauer, R., Oelzant, S., Fringeli, U.P., Ecker, G.F., Noe, C.R.:"A flow based hollow-fiber blood-brain barrier in vitro model with immortalised cell line PBMEC/C1-2", posterpresentation at the Gordon Research Conference "Barries of the CNS", Tilton School, Tilton (NH, USA), June 25-30, 2006.
  • Neuhaus, W., Trzeciak, J., Lachmann, B., Noe, C.R.: "APTS-labeled dextrans: A new tool for characterizing cell layer's tightness", posterpresentation on "Peripheral markers of Blood-brain barrier failure III symposium", Cleveland (Ohio, USA) November 2004, Abstract in: Syllabus (2004).
  • Neuhaus W., Vienna/A, Trzeciak, J., Vienna/A, Lauer, R., Vienna/A, Lachmann, B., Vienna/A, Noe, C.R., Vienna/A: "Tightness Determination of two Blood-Brain Barrier Models: Correction by means of Capillary gel electrophoresis", posterpresentation on the Analytica 2004 conference, Munich 2004, Abstract in: http://va.gdch.de/wwwdata/abstracts/5553/5553_0178.pdf
  • W. Neuhaus, R. Lauer, G.F. Ecker, C.R. Noe: “Ein dynamisches in vitro Modell der Blut-Hirn Schranke”, posterpresentation on the 17th Scientific Congress of the Austrian Pharmaceutical Society, Graz 2003; Abstract in: Sci. Pharm. 71, S61 (2003).
  • T. Mayrhofer, W. Neuhaus, R. Lauer, G.F. Ecker, C.R. Noe: “Permeationsstudien einer Reihe von Glycin-Antagonisten an einem in vitro Modell der Blut-Hirn Schranke”, posterpresentation on the 17th Scientific Congress of the Austrian Pharmaceutical Society, Graz 2003; Abstract in: Sci. Pharm. 71, S60 (2003).
  • J. Kainz, R. Lauer, W. Neuhaus, C.R. Noe, G.F. Ecker: “Physikochemische Charakterisierung einer Reihe von Glycinantagonisten zur Abschätzung ihrer Permeationseigenschaften in der Blut-Hirn Schranke”, posterpresentation on the 17th Scientific Congress of the Austrian Pharmaceutical Society, Graz 2003; Abstract in: Sci. Pharm. 71, S57 (2003).
  • Novalin, S., Neuhaus, W., Weber, A. Kulbe, K.D.: Entwicklung eines neuartigen Enzym-Membranreaktors zur Hydrolyse von Lactose im Industriemaßstab.. In: Univ. f. Bodenkultur Wien, Tschechische Agraruniversität Prag, Univ. Westungarn (Hrsg.): Tagungsband, Boku-Kongress 'Leben und Überleben - Konzepte für die Zukunft', Abstracts, 219. 19-21 November 2001, Hofburg, Wien (2001).