We are currently working to update and streamline techniques for 3D imaging of molecular probes in whole samples.
Chick embryo immunostained for acetylated α-tubulin, contrasted with peroxidase-mediated reduced silver deposition. Metscher and Müller 2011, Dev Dyn 240:2301.
Canine skin lesion hemisected vertically. Virtual sections near the common (cut) surface (9µm voxels). L: Lugol staining, favours keratin, adipose tissue. R: PTA staining - favours collagen, connective tissue. Collaboration with Dr. R. Doughty, AHUS, Oslo.