Univ.-Ass. Dr. Dipl.-Biol.(t.o.) Thomas Nägele

Department of Ecogenomics and Systems Biology
University of Vienna
Althanstr. 14
1090 Vienna, Austria

T: (+43)-1-4277-76556
F: (+43)-1-4277-9577
email: thomas.naegele@univie.ac.at

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Research Focus:

 
The experimental high-throughput analysis of cellular systems has become an integral part of biological research.Concomitantly, the interpretation of the resulting complex data sets with respect to biochemical regulation and physiological traits lags far behind.

My group's research focus addresses the question how to link such experimental high-throughput data to underlying biochemical and signalling networks, their regulation and related physiological traits. The compilation of our biochemical, physiological and high-throughput techniques are combined with a framework of biomathematical procedures and workflows ultimately aiming at the detection and characterisation of molecular physiological outputs.

  

Key Techniques:

 
Metabolomics (see also: ViMe - Vienna Metabolomics Center)

Subcellular fractionation techniques

Enzyme kinetics

Mathematical modeling of metabolic networks

Multivariate Statistics

Time Series Analysis