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2003
- W. Neuhaus, R. Lauer, G.F. Ecker, C.R. Noe:
“Ein dynamisches in vitro Modell der Blut-Hirn Schranke”,
posterpresentation on the 17th Scientific Congress of the Austrian Pharmaceutical
Society, Graz 2003; Abstract in: Sci. Pharm. 71, S61 (2003).
- T. Mayrhofer, W. Neuhaus, R. Lauer, G.F. Ecker,
C.R. Noe: “Permeationsstudien einer Reihe von Glycin-Antagonisten
an einem in vitro Modell der Blut-Hirn Schranke”, posterpresentation
on the 17th Scientific Congress of the Austrian Pharmaceutical Society,
Graz 2003; Abstract in: Sci. Pharm. 71, S60 (2003).
- R. Lauer, J. Kainz, G.F. Ecker, C.R. Noe: “Anwendung
eines in vitro Modells der Blut-Hirn Schranke: Transportstudien mit
nichtsteroidalen Antirheumatika”, posterpresentation on the 17th
Scientific Congress of the Austrian Pharmaceutical Society, Graz 2003;
Abstract in: Sci. Pharm. 71, S59 (2003).
- D. Kaiser, L. Terfloth, S. Kopp, J.C.C. Schultz,
R.C. de Laet, P. Chiba, G.F. Ecker, J. Gasteiger: “In silico screening
der SPECS-Datenbank zur Identifizierung neuer Modulatoren der Multidrug-Resistenz”,
posterpresentation on the 17th Scientific Congress of the Austrian Pharmaceutical
Society, Graz 2003; Abstract in: Sci. Pharm. 71, S32 (2003).
- D. Kaiser, G.F. Ecker: “Ähnlichkeitsbasierte
Deskriptoren zur Vorhersage von ADME-Parametern”, posterpresentation
on the 17th Scientific Congress of the Austrian Pharmaceutical Society,
Graz 2003; Abstract in: Sci. Pharm. 71, S33 (2003).
- J. Kainz, R. Lauer, W. Neuhaus, C.R. Noe, G.F.
Ecker: “Physikochemische Charakterisierung einer Reihe von Glycinantagonisten
zur Abschätzung ihrer Permeationseigenschaften in der Blut-Hirn
Schranke”, posterpresentation on the 17th Scientific Congress
of the Austrian Pharmaceutical Society, Graz 2003; Abstract in: Sci.
Pharm. 71, S57 (2003).
- D. Kaiser, P. Chiba, S. Kopp, J. Gasteiger,
L. Terfloth, G. Ecker: “Self-organising maps for identification
of new inhibitors of P-glycoprotein”, posterpresentation on the
4th FEBS Advanced Lecture Course “ATP-Binding Cassette (ABC) Proteins:
From Genetic Disease to Multidrug Resistance”, Gosau 2003.
- E. Csaszar, G. Ecker, S. Kopp, K. Pleban, P.
Chiba: “Photoaffinity labeling and peptide mass spectrometry in
the characterization of ligand binding domains of ABC-transporters”,
posterpresentation on the 4th FEBS Advanced Lecture Course “ATP-Binding
Cassette (ABC) Proteins: From Genetic Disease to Multidrug Resistance”,
Gosau 2003.
2002
- S. Kopp, E. Csaszar, G.F. Ecker, K. Pleban,
D. Kaiser, P. Chiba: “Characterization of the substrate binding
domain of drug efflux pumps by photoaffinity labeling and mass spectrometry”,
posterpresentation on the Annual Meeting of the Austrian Biochemical
Society, 2002
- G. Ecker, D. Kaiser, P. Chiba: "A VolSurf
model of propafenone-type modulators of multidrug resistance",
posterpresentation at the 7th European Congress of Pharmaceutical Sciences,
Stockholm 2002; Abstract in: Eur. J. Pharm. Sci. 17 (Suppl. 1), S79
(2002).
- R. Lauer, G. Ecker, C.R. Noe: "Permeation
of a set of benzodiazepines across an in vitro blood-brain barrier model",
posterpresentation at the 7th European Congress of Pharmaceutical Sciences,
Stockholm 2002; Abstract in: Eur. J. Pharm. Sci. 17 (Suppl. 1), S114
(2002).
- R. Lauer, B. Dampier, G. Ecker, C.R. Noe: "The
excitatory amino acid transport system EAAT2 and EAAT3 of an in vitro
model of the blood brain barrier", posterpresentation at the 7th
European Congress of Pharmaceutical Sciences, Stockholm 2002; Abstract
in: Eur. J. Pharm. Sci. 17 (Suppl. 1), S113 (2002).
- G. Ecker, C. Gallhuber, R. Lauer, C.R. Noe:
"Artificial membrane permeation of a series of benzodiazepines",
posterpresentation at the 7th European Congress of Pharmaceutical Sciences,
Stockholm 2002; Abstract in: Eur. J. Pharm. Sci. 17 (Suppl. 1), S100
(2002).
- D. Niepel, T. Pöhler, M.L. Berger, G.
Ecker, C.R. Noe: "Polyaminamide-derivatives with different pharmacological
effects at the NMDA receptor as tools in drug research", posterpresentation
at the 7th European Congress of Pharmaceutical Sciences, Stockholm 2002;
Abstract in: Eur. J. Pharm. Sci. 17 (Suppl. 1), S81 (2002).
- D. Kaiser, S. Kopp, L. Terfloth, R.C. de Laet,
J.C.C. Schultz, P. Chiba, G.F. Ecker, J. Gasteiger: "Self-organising
maps for identification of new lead compounds from the SPECS database",
posterpresentation on The New Chemistries, Delft 2002
- P. Cledera, C. Avendano, P. Chiba, S. Kopp,
G. Ecker, J.C. Menendez: "Synthesis and anti-MDR activity of arylmethylene
derivatives of the pyrazino[2,1-b]quinazoline-3,6-dione system",
posterpresentation on the XVIIth International Symposium on Medicinal
Chemistry, Barcelona 2002; Abstract in: Drugs Fut. 27 (Suppl. A), 118
(2002).
- C. Klein, D. Kaiser, S. Kopp, P. Chiba, G.F.
Ecker: "Similarity-based structure-activity relationships (SIBAR)
as tool for early ADMET profiling", oral communication on the XVIIth
International Symposium on Medicinal Chemistry, Barcelona 2002; Abstract
in: Drugs Fut. 27 (Suppl. A), 69 (2002).
- K. Pleban, S. Kopp, P. Chiba, G.F. Ecker: "Design
and synthesis of benzophenone derivatives for photoaffinity labenling
studies with P-glycoprotein", posterpresentation on the XVIIth
International Symposium on Medicinal Chemistry, Barcelona 2002; Abstract
in: Drugs Fut. 27 (Suppl. A), 404 (2002).
- D. Kaiser, L. Terfloth, S. Kopp, J. Schultz,
R. de Laet, P. Chiba, G.F. Ecker, J. Gasteiger: "Analysis od a
data-set of 131 MDR-modulators with self organizing maps and in silico
screening of the SPECS database", posterpresentation on the XVIIth
International Symposium on Medicinal Chemistry, Barcelona 2002; Abstract
in: Drugs Fut. 27 (Suppl. A), 294 (2002).
- G. F. Ecker, P. Chiba, C. R. Noe: "In
silico screening with benzofurane and benzopyrane-type MDR-modulators",
short lecture on the Xth Symposium on Heterocyclic Structures in Medicinal
Chemistry, Palermo 2002
- B. Linz, G. Ecker, C.R. Noe: "pH-metrische
Bestimmung der logP-Werte von H1-Antihistaminika", posterpresentation
on the Analytika 2002, Munich 2002
2001
- S. Kopp, G.F. Ecker, E. Csaszar, B. Plagens,
W. Holzer, M. Hitzler, P. Chiba: “Identification of ligand-binding
regions of P-glycoprotein by activated-pharmacophore photoaffinity laebling
and MALDI-TOF mass spectrometry”, posterpresentation on the Annual
Meeting of the Austrian Biochemical Society, 2001.
- R. Lauer, G. Jost, G.F. Ecker, C.R. Noe: "Optimierung eines
in vitro Blut-Hirn-Schranken Modells", posterpresentation on the
16th Scientific Congress of the Austrian Pharmaceutical Society, Vienna
2001; Abstract in: Sci. Pharm. 69 (Suppl. 1), S89 (2001).
- S. Iordanova, G. Haberhauer, G. F. Ecker, C.
R. Noe: "Molecular Modelling Studies on modified Antisense Nucleotides",
posterpresentation on the 16th Scientific Congress of the Austrian Pharmaceutical
Society, Vienna 2001; Abstract in: Sci. Pharm. 69 (Suppl. 1), S328 (2001).
- D. Kaiser, L. Terfloth, P. Chiba, G. F. Ecker,
J. Gasteiger: "Analyse eines Datensatzes von 131 MDR-Modulatoren
mit Hilfe von Selbstorganisierenden Karten", posterpresentation
on the 16th Scientific Congress of the Austrian Pharmaceutical Society,
Vienna 2001; Abstract in: Sci. Pharm. 69 (Suppl. 1), S95 (2001).
- C. T. Klein, D. Kaiser, P. Chiba, G. F. Ecker:
"Entwicklung neuer Deskriptoren auf Basis von Ähnlichkeitsanalysen",
posterpresentation on the 16th Scientific Congress of the Austrian Pharmaceutical
Society, Vienna 2001; Abstract in: Sci. Pharm. 69 (Suppl. 1), S93 (2001).
- T. Müller-Uri, J. F. Sarfo, S. Kopp, P.
Chiba, G. F. Ecker: "Synthese und MDR-Modulierende Aktivität
von 5-Methyl-substituierten Propafenon-Analoga", posterpresentation
on the 16th Scientific Congress of the Austrian Pharmaceutical Society,
Vienna 2001; Abstract in: Sci. Pharm. 69 (Suppl. 1), S56 (2001).
- P. Wetwitayaklung, S. Kopp, P. Chiba, G. F.
Ecker: "Synthesis and MDR-modulating activity of enantiopure benzopyrano[3,4-b][1,4]oxazines",
posterpresentation on the 16th Scientific Congress of the Austrian Pharmaceutical
Society, Vienna 2001; Abstract in: Sci. Pharm. 69 (Suppl. 1), S58 (2001).
- G. F. Ecker, P. Chiba, C. Klein, D. Kaiser:
"Descriptors based on similarity measures für QSAR studies
of inhibitors of P-glycoprotein", posterpresentation on the 222nd
National Meeting of the American Chemical Society, Chicago 2001
- G. F. Ecker, P. Wetwitayaklung, P. Chiba: "Hologram
QSAR analysis of benzopyrane-type modulators of multidrug resistance",
posterpresentation on the 222nd National Meeting of the American Chemical
Society, Chicago 2001
- C. Klein, D. Kaiser, P. Chiba, G. Ecker: "Similarity-based
descriptors for QSAR-studies of modulators of multidrug resistance",
posterpresentation and short talk on the 13th Noordwijkerhout-Camerino
Symposium "Trends in Drug Research", Noorwijkerhout, May 2001
- P. Chiba, S. Kopp, G.F. Ecker, M. Smiesko,
D. Kaiser: "Comparative molecular field analysis (CoMFA) and comparative
molecular similarity analysis (CoMSIA) of propafenone-type modulators
of multidrug resistance", posterpresentation on the 92nd Annual
Meeting of the American Association for Cancer Research, Chicago 2001;
Abstract in: Proc. Am. Assoc. Canc. Res. 42, 949 (2001)
- G. Ecker, B. Plagens, W. Holzer, S. Kopp, E.
Csazar, P. Chiba: "Pharmacophore photoactivation of propafenone-type
Pgp-inhibitors as a tool for the identification of interacting protein
peptide fragments", posterpresentation on the 3rd FEBS Advanced
Lecture Course "ATP Binding Cassette (ABC) Transporters: From Multidrug
Resistance to Genetic Disease", Gosau, Mar. 2001
2000
- G. Ecker, P. Chiba, M. Eder, T. Langer, R.
Hoffmann: "A chemical function based pharmacophore model of propafenone-type
MDR-modulators", posterpresentation on the International Symposium
"Oncology: New Aspects", Schliersee, Oct. 2000
- R. Bauer, R. Lauer, B. Linz, G. Ecker, P. Friedl,
C.R. Noe: "Development of an in vitro blood-brain barrier model
based on immortalized porcine PBMEC/C1-2 cells", posterpresentation
on the 6th Eurpean Congress of Pharmaceutical Sciences, EUFEPS 2000,
Budapest, Sept. 2000; Abstract in: Eur. J. Pharm. Sci. 11/Suppl. 1:
S105 (PO-219), 2000
- G. Ecker, B. Plagens, W. Holzer, S. Kopp, P.
Chiba: "QSAR studies of low molecular weight ligands suitable for
activated pharmacophore photoaffinity labeling of P-glycoprotein",
posterpresentation on the Jahrestagung der Österreichischen Biochemischen
Gesellschaft, Innsbruck, Sept. 2000
- D. Kaiser, P. Chiba, G. Ecker: "Hologram
QSAR analysis of propafenone-type modulators of multidrug resistance",
posterpresentation on the XVIth International Symposium on Medicinal
Chemistry, Bologna, Sept. 2000
- M. Smiesko, P. Chiba, G. Ecker: "Comparative
molecular field and comparative molecular similarity analysis of propafenone-type
modulators of multidrug resistance", posterpresentation on the
XVIth International Symposium on Medicinal Chemistry, Bologna, Sept.
2000
- P. Wetwitayaklung, P. Chiba, G. Ecker: "Synthesis
and mdr-modulating activity of enantiopure 1-benzopyrano[3,4-b][1,4]oxazines",
posterpresentation on the XVIth International Symposium on Medicinal
Chemistry, Bologna, Sept. 2000
- G. Ecker, H. Kalchhauser, W. Mikenda, P. Wolschann:
"NMR spectroscopy and ab initio calculations: a comparison between
experimental and theoretical results", lecture on the 22. Diskussionstagung
der Fachgruppe "Magnetische Resonanzspektroskopie" der Gesellschaft
Deutscher Chemiker, Regensburg, Germany, Sept. 2000
- G. Ecker, P. Chiba, M. Eder, T. Langer, R.
Hoffmann, J. Drach: "A chemical function based pharmacophore model
of propafenone-type MDR-modulators”, posterpresentation on the
91st Annual Meeting of the American Association for Cancer Research,
San Francisco 2000; Abstract in the 91st Proceedings, p 762, nr. 4841
- G. Ecker: “Development and Design of
New Inhibitors of Drug Efflux Pumps”, invited lecture on the 4th
Annual National Symposium on Computational Science and Engineering,
Bangkok 2000
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