Mission statement

We pursue to unravel some molecular aspects of early mammalian cardiomyogenesis. We are interested in signaling and genetic regulation of commitment and differentiation of cardiac stem cells and the transcriptional balancing of self-renewal and differentiation in adult cardiac stem cells. From the 400+ genes involved in early cardiomyogenesis we focus on the matricellular protein SPARC and the intermediate filament protein Desmin and study their role and interaction in murine cardiac stem cell lines. (14.4.2022)